Association of gene expression involving innate immunity and genetic variation in IL28B with antiviral response.
Hepatology. 2011; 55(1):20-29.
IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C.
J Infect Dis. 2011; 204(1): 84-93.
Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders.
Hepatology. 2012; 55(3): 742-748.
Let-7b is a novel regulator of hepatitis C virus replication.
Cell Mol Life Sci. 2012;69(15):2621-33.
Efficacy of therapy for advanced hepatocellular carcinoma: intra-arterial 5-fluorouracil and subcutaneous interferon with image-guided radiation.
J Gastroenterol Hepatol. 2011; 26(7): 1123-1132.
Inhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Haliclona (Reniera) sp.
Plos One. 2012; 7(11): e48685.
A large-scale nationwide multicenter prospective observational study of triple therapy using rabeprazole, amoxicillin, and clarithromycin for Helicobacter pylori eradication in Japan
Journal of Gastroenterology. 2012; 47(3): 276-283.
Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 91.
J Virol. 2011; 85(12):5986-5994.
Triple Therapy with Ecabet Sodium, Amoxicillin and Lansoprazole for 2 Weeks as the Rescue Regimen for H. pylori Infection.
Intern Med. 2011; 50(5): 369-374.
Sustained-release adrenomedullin ointment accelerates wound healing of pressure ulcers.
Regulatory Peptides. 2011; 168(1-3): 21-26.
Clinical impact of cycling administration of antibiotics for febrile neutropenia in Japanese patients with hematological malignancy.
Eur J Clin Microbiol Infect Dis. 2012; 31(2): 173-178.
Stent selection and tips on placement technique of EUS-guided biliary drainage: transduodenal and transgastric stenting
J Hepatobiliary Pancreat Sci. 2011; 18(5): 664-672.
Evaluation of effects of a novel endoscopically applied radiofrequency ablation biliary catheter using an ex-vivo pig liver.
J Hepatobiliary Pancreat Sci. 2012; 19(5): 543-547.
Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture.
Nat Protoc. 2012; 7(2): 235-246.
Adjuvant therapy with imatinib mesylate after resection of primary high-risk gastrointestinal stromal tumors in Japanese patients.
Int J Clin Oncol. 2011; ♂EPub ahead of Print♀
Professional oral health care reduces oral mucositis and febrile neutropenia in patients treated with allogeneic bone marrow transplantation.
Support Care Cancer. 2012; 20(2): 367-373.
Phase II study of chemoradiotherapy with 5-fluorouracil and cisplatin for Stage II-III esophageal squamous cell carcinoma: JCOG trial (JCOG 9906).
Int J Radiat Oncol Biol Phys. 2011; 81(3): 684-690.
Preoperative biliary drainage for hilar cholangiocarcinoma: which stent should be selected?
J Hepatobiliary Pancreat Sci. 2011; 18(5): 630-635.
A muticenter prospective randomized study of selective bile duct cannulation performed by multiple endoscopists: The BIDMEN study
Gastointestinal Endoscopy. 2012; 75(2): 362-372.
Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C.
J Gastroenterol. 2012; 47(11): 1228-1237.
Phase II study of combined treatment with irinotecan and S-1 (IRIS) in patients with inoperable or recurrent advanced colorectal cancer (HGCSG0302).
Oncology. 2011; 80(1): 70-75.
Randomized phase II trial of first-line treatment with tailored irinotecan and S-1 therapy versus S-1 monotherapy for advanced or recurrent gastric carcinoma (JFMC31-0301).
Anticancer Drugs. 2011; 22(6): 576-583.
Age and total ribavirin dose is an independent predictor of relapse among early virological responders to peg-interferon plus ribavirin therapy in chronic hepatitis C revealed by data mining analysis.
Antivir Ther. 2012; 17:35-43.
Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C.
J Hepatol. 2012;56(3):602-608.
Sequences in the interferon sensitivity-determining region and core region of hepatitis C virus impact pretreatment prediction of response to PEG-interferon plus ribavirin: data mining analysis.
J Med Virol. 2011;83:445-452.
A model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated-interferon plus ribavirin therapy for chronic hepatitis C.
J Med Virol. 2013; ♂in press♀.
Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication.
Antimicrob Agent Chemother. 2012; 56(3):1315-1323.
Carbon dioxide insufflation during endoscopic retrograde cholangiopancreatography reduces bowel gas volume but does not affect visual analogue scale scores of suffering: a prospective, double-blind, randomized, controlled trial.
Surgical Endoscopy. 2011; 25(12): 3784-3790.
Cyclophilin A and nuclear factor of activated T cells are essential in cyclosporin A-mediated suppression of polyomavirus BK replication.
Am J Transplantation. 2012; 12: 2348-2362.
Combination of hepatitis B viral antigens and DNA for prediction of relapse after discontinuation of nucleos(t)ide analogs in patients with chronic hepatitis B.
Hepatology Research. 2012; 42(2): 139-149.
Phase I dose-escalating study of panobinostat (LBH589) Administered intravenously to Japanese patients with advanced solid tumors.
Invest New Drugs. 2012; 30(5): 1950-1957.
Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C.
Hepatol Int. 2012; ♂EPub ahead of Print♀.
Gene and protein expression analysis of mesenchymal stem cells derived from rat adipose tissue and bone marrow.
Circulation Journal. 2011; 75(9): 2260-2268.
Relationship Between Diffusion-Weighted Magnetic Resonance Imaging and Histological Tumor Grading of Hepatocellular Carcinoma.
Ann Surg Oncol. 2012; 19(4): 1302-1309.
Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.
Eur J Med Chem. 2012; 49:191-199.
Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immunity.
Hepatology. 2012; ♂EPub ahead of Print♀.
A Notch3-mediated squamous cell differentiation program limits expansion of EMT competent cells that express the ZEB transcription factors.
Cancer Res. 2011; 71(21): 6836-6847.
Macrophage migration inhibitory factor contributes to development of nonsteroidal anti-inflammatory drugs-induced gastric injury in mice.
Int Immunopharmacol. 2011; 11(4): 418-423.
EUS-FNA for suspected malignant biliary strictures after negative endoscopic transpapillary brush cytology and forceps biopsy.
J Gastroenterol. 2011; 46(7): 921-928.
Target biopsy using magnifying endoscopy in clinical management of gastric mucosa-associated lymphoid tissue lymphoma.
J Gastroenterol Hepatol. 2011; 26(7): 1133-1138.
Endoscopic ultrasound-guided transmural drainage for pancreatic fistula or pancreatic duct dilatation after pancreatic surgery.
Surgical Endoscopy. 2012; 26(17): 1710-1717.
The 8p11 myeloproliferative syndrome owing to rare FGFR1OP2-FGFR1 fusion.
Eur J Haematol. 2011; 86(4): 347-349.
A multi-center survey of re-treatment with pegylated interferon plus ribavirin combination therapy for patients with chronic hepatitis C in Japan.
Hepatol Res. 2012; ♂in press♀.
Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients.
J Gastroenterol. 2011; 46(7): 929-937.
10-Gingerol, a component of rikkunshito, improves cisplatin-induced anorexia by inhibiting acylated ghrelin degradation.
Biochem Biophys Res Commun. 2011; 412(3): 506-511.
Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a.
Virus Research. 2012; 165(2):214-218
Decreased motility of the lower esophageal sphincter in a rat model of gastroesophageal reflux disease may be mediated by reductions of serotonin and acetylcholine signaling.
Biol Pharm Bull. 2011; 34(5): 704-711.
Decreased plasma ghrelin contributes to anorexia following novelty stress.
Am J Physiol Endocrinol Metab. 2011; 301(4): E685-696.
Phase I study of concurrent real-time tumor-tracking thoracic radiation therapy with paclitaxel and carboplatin in locally advanced non-small cell lung cancer.
Lung Cancer. 2011; 74(2): 248-252.
Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b.
J Med Virol. 2011;83:871-878.
"Romiplostim for the treatment of chronic immune thrombocytopenia in adult Japanese patients: a double-blind, randomized Phase III clinical trial."
Int J Hematol. 2011; 94(1): 71-80.
Sensitivity to previous irinotecan treatment does not predict the efficacy of combination chemotherapy with cetuximab plus irinotecan for wild-type KRAS metastatic colorectal cancer.
Eur J Cancer. 2011; 47(18): 2673-2680.
Endoscopic pancreatic duct stents reduce the incidence of post-endoscopic retrograde cholangiopancreatography pancreatitis in high risk patients
Clin Gastroenterol Hepatol. 2011; 9(10): 851-858.
Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study.
Jpn J Clin Oncol. 2011; 41(4): 487-490.
Efficacy of folic acid in preventing oral mucositis in allogeneic stem cell transplant patients receiving MTX as prophylaxis for GVHD.
Bone Marrow Transplant. 2012; 47(2): 258-264.
Inhibition of hepatitis C virus replication and viral helicase by ethyl acetate extract of the marine feather star Alloeocomatella polycladia.
Marine Drugs. 2012; 10(4):744-61.